Hypochromia (Hypo) - Siemens ADVIA 2120 Operator's Manual

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The %HYPER value is intended for flagging and laboratory purposes only.
Results Flagged
none
Possible Causes
The following list of sample-related causes may not contain all conditions that
could cause this flag.
Multiple occurrences of this flag, especially for consecutive samples, can indicate
a system problem. However, isolated instances of this flag are usually sample
related.
Sample Related
Hereditary spherocytosis
Sickle cell anemia
Hemolytic uremic
syndrome

Hypochromia (HYPO)

Definition
The Hypochromia flag is triggered if the percentage of cells with low cellular
hemoglobin concentration (%HYPO) is equal to or greater than 4.0%.
The %HYPO parameter indicates the percent of cells that have a cellular
hemoglobin concentration less than 28 g/dL and is derived from the RBC HC
histogram.
Default trigger values for the three severity levels are:
+
++
+++
The %HYPO value is intended for flagging and laboratory purposes only.
Results Flagged
none
Possible Causes
The following list of sample-related causes may not contain all conditions that
could cause this flag.
Multiple occurrences of this flag, especially for consecutive samples, can indicate
a system problem. However, isolated instances of this flag are usually sample
related.
Flags
%HYPO = 4.0% to 7.9%
%HYPO = 8.0% to 12.0%
%HYPO% > 12.0%
System Related
1. Check RBC reagents.
2. Check the laser sample delivery.
3. Check the RBC gains.
4. Check the laser flowcell alignment
6-9
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Advia 2120i

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